CLINICAL PAPERS

BodyFX for Long-Term Fat Reduction

A Clinical and Biological Evaluation of a Novel, Noninvasive Radiofrequency Device for the Long-Term Reduction of Adipose Tissue

Author:
Sylvie Boisnic, MD; Marc Divaris, MD; Andrew A. Nelson, MD; Nima M. Gharavi, MD, PhD; and Gary P. Lask, MD
Publication & Date:
Lasers in Surgery and Medicine | February, 2014
Technology:
BodyFX/MiniFX

SUMMARY

Abstract
This study evaluated BodyFX, a novel noninvasive radiofrequency (RF) device using suction-coupled heating and ultra-short pulse duration energy for long-term reduction of subcutaneous fat. Twenty-one patients underwent six weekly abdominal treatments, with outcomes measured by circumference, ultrasound, adipose weight, and histology. Significant reductions were observed in abdominal circumference, fat thickness, and adipose tissue weight. Histologic analysis demonstrated decreased adipocyte size, increased apoptosis, and enhanced collagen synthesis with dermal remodeling.

Conclusion
The findings confirm that BodyFX is a safe and effective noninvasive treatment for reducing adipose tissue while promoting skin tightening. Improvements were maintained at 1- and 3-month follow-ups, with histologic evidence of apoptosis-driven fat reduction and neocollagenesis. The device addresses both subcutaneous fat and dermal quality, making it a valuable option for long-term body contouring.

TOPICS COVERED

  • Clinical evaluation of BodyFX for noninvasive fat reduction
  • Abdominal circumference and subcutaneous fat thickness reduction outcomes
  • Ultrasound and histologic confirmation of adipocyte apoptosis
  • Evidence of neocollagenesis and dermal remodeling (skin tightening)
  • Long‑term safety and efficacy maintained at 1–3 month follow‑ups

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