CLINICAL PAPERS

InMode's TiteFX for Noninvasive Body Contouring

Non-Surgical Body Contouring: Introduction of a New Non-Invasive Device for Long-Term Localized Fat Reduction and Cellulite Improvement Using Controlled, Suction Coupled, Radiofrequency Heating and High Voltage Ultra-Short Electrical Pulses

Author:
Stephen Mulholland, MD; and Michael Kreindel, PhD
Publication & Date:
Clinical & Experimental Dermatology Research | September, 2012
Technology:
BodyFX/MiniFX

SUMMARY

Abstract
This prospective study evaluated TiteFX, a novel noninvasive device combining radiofrequency heating with high-voltage electrical pulse fields to reduce adipose tissue and tighten skin. Patients underwent a series of abdominal treatments, assessed through circumference measurements, ultrasound, histology, and electron microscopy. Results demonstrated significant adipocyte apoptosis, reduced fat layer thickness, and improvements in dermal collagen remodeling. Clinical observations confirmed visible circumferential reduction and enhanced skin tone.

Conclusion
TiteFX proved to be a safe and effective modality for noninvasive body contouring by reducing subcutaneous fat and improving skin quality. The dual mechanism of RF-induced heating and pulsed electrical fields enhances adipocyte apoptosis and neocollagenesis, positioning TiteFX as a comprehensive solution for patients seeking body contouring without surgery.

TOPICS COVERED

  • Introduction of TiteFX for noninvasive body contouring
  • Mechanism: RF heating combined with electrical pulse fields
  • Clinical results: circumferential reduction and fat thickness decrease
  • Histology and electron microscopy confirming adipocyte apoptosis
  • Evidence of neocollagenesis and dermal remodeling for skin tightening
  • Favorable safety profile and patient tolerability

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