CLINICAL PAPERS

Collagen and Elastin Regeneration in Acne Scars

Novel Histological Evidence of Collagen and Elastin Regeneration in Fractional RF-Treated Acne Scars

Author:
Hellman, J., & Yao, J.
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Technology:
Morpheus8

SUMMARY

Abstract
This study evaluated the long-term histological effects of fractional radiofrequency (FRF) microneedling (Fractora, InMode) on acne scars. Patients underwent four treatments, and biopsies were taken before, after treatment, and 3.5 years post-treatment. Histological analysis demonstrated significant dermal remodeling, including regeneration of elastic fibers, collagen deposition, and scar tissue reduction. Patient samples revealed scar depth reduction of up to 80%, with lasting improvements in skin architecture and clinical appearance.

Conclusion
Fractional RF microneedling provides safe, long-term correction of acne scars through deep dermal remodeling and regeneration of collagen and elastin. Results sustained 3.5 years post-treatment confirm its durable efficacy. The study establishes fractional RF as a leading modality for acne scar treatment with superior long-term outcomes compared to conventional resurfacing methods.

TOPICS COVERED

  • Histological evaluation of Fractora fractional RF on acne scars
  • Long-term follow-up (3.5 years) showing sustained results
  • Collagen deposition and elastic fiber regeneration
  • Scar depth reduction up to 80% post-treatment
  • Clinical improvements in scar appearance, pores, and texture
  • Advantages of FRF over traditional laser resurfacing for scar revision

RELATED CONTENT

Morpheus8 Fractional RF for Acne and Scar Reduction

The Role of Fractional Radiofrequency in Long-term Acne Remission and Reduction of Acne Scar Load

Author:
Fadi Hamadani, MD, and Neil M. Vranis, MD
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Clinical Study on RF-Assisted Facial Rejuvenation

An Anatomical Approach to Radiofrequency-Assisted Facial Rejuvenation: Beyond the Treatment Gap

Author:
Michael J. Stein, MD, MAS, FRCSC, FACS, Neil M. Vranis, MD, and Sherrell J. Aston, MD, FACS
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
High Definition Body Contouring using BodyTite Liposuction and Morpheus8

Body Contouring Finesse: Dynamic Definition Liposculpture and Bipolar Radiofrequency Microneedling

Author:
Alfredo E. Hoyos, MD, Mauricio E. Perez Pachon, MD, and Neil M. Vranis, MD
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Morpheus8 RF for Anti-Aging Skin Rejuvenation

Correction of age-related changes in the skin at the dermal and subdermal level using radiofrequency macroneedling therapy

Author:
Elena Flegontova, MD, Michael Kreindel, MD, Neil M. Vranis, MD, R. Stephen Mulholland, MD.
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Morpheus8 as a Treatment for HA Filler Complication

Post-Hyaluronic Acid Recurrent Eyelid Edema: Pathophysiologic Mechanisms and a Proposed Treatment Protocol

Author:
Justin Karlin, MD, MS, Neil Vranis, MD, Erez Dayan, MD & Kami Parsa, MD
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Ancillary Procedures to Facelift Surgery: What has Changed?

Ancillary Procedures to Facelift Surgery: What has Changed?

Author:
Michael J. Stein, MD, MAS, FRCSC; and Sherrell J. Aston, MD, FACS.
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Study: Morpheus8 RF for Aesthetic Skin Tightening

Introduction and overview of radiofrequency treatments in aesthetic dermatology

Author:
Axel R. Delgado MD, Anne Chapas MD
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
Study: Morpheus8 & AccuTite for Post-Facelift Laxity

The Use of Radiofrequency-Assisted Lipolysis with Radiofrequency Microneedling in Premature Jowl and Neck Laxity Following Facialplasty

Author:
Daniel Demesh, MD; Robert T. Cristel, MD; Nimit D. Gandhi, MD; Eljona Kola, MS; Steven H. Dayan MD, FACS
Publication & Date:
Journal of Cosmetics, Dermatological Sciences and Applications | June, 2019
 Disclaimer

DISCLAIMER

InMode University is an international resource for providers to expand their understanding through online presentations. While every effort is made to ensure that the content posted by us online is current and accurate, we accept no liability for the content, accuracy, completeness or currency of that information and disclaim all liability to any person in relation to, or, in the use of, the information or data.

Physician presenters are independent contractors. InMode does not take responsibility for education provided by the independent physician proctors. InMode does not endorse any particular physician. Statements provided by physicians appearing during this training about InMode products are based on the individual experiences of those individuals. InMode does not endorse the settings discussed by any particular physician. Your individual experiences may vary. Any of those statements are those of the individuals making them and do not reflect to opinions or views of InMode, its parent or affiliate companies or any of their contractors.